Detalhe da pesquisa
1.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 184(18): 4651-4668.e25, 2021 09 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450028
2.
Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic.
Cell
; 187(6): 1565-1566, 2024 Mar 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490183
3.
Does dual-energy abdominal computed tomography increase the radiation dose to patients: a prospective observational study.
Pol J Radiol
; 86: e208-e216, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34093917
4.
High-Throughput Liquid Chromatography-Tandem Mass Spectrometry Quantification of Glycosaminoglycans as Biomarkers of Mucopolysaccharidosis II.
Int J Mol Sci
; 21(15)2020 Jul 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-32751752
5.
Discovery and bio-optimization of human antibody therapeutics using the XenoMouse® transgenic mouse platform.
Immunol Rev
; 270(1): 51-64, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864104
6.
Engineering an IgG Scaffold Lacking Effector Function with Optimized Developability.
J Biol Chem
; 292(5): 1865-1875, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994062
7.
Biological Characterization of a Stable Effector Functionless (SEFL) Monoclonal Antibody Scaffold in Vitro.
J Biol Chem
; 292(5): 1876-1883, 2017 02 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27994063
8.
A novel antibody engineering strategy for making monovalent bispecific heterodimeric IgG antibodies by electrostatic steering mechanism.
J Biol Chem
; 290(12): 7535-62, 2015 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25583986
9.
Asymmetrical Fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies.
J Biol Chem
; 289(6): 3571-90, 2014 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-24311787
10.
Cigarette butt pollution in popular beaches of Morocco: Abundance, distribution, and mitigation measures.
Mar Pollut Bull
; 195: 115530, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37717497
11.
Role of advanced (magnetic resonance) neuroimaging and clinical outcomes in neonatal strokes: Experience from tertiary care center.
Neuroradiol J
; 36(3): 297-304, 2023 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-36170618
12.
Personal protective equipment (PPE) pollution driven by the COVID-19 pandemic in coastal environment, Southeast Coast of India.
Mar Pollut Bull
; 180: 113769, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35609465
13.
Molecular architecture determines brain delivery of a transferrin receptor-targeted lysosomal enzyme.
J Exp Med
; 219(3)2022 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35226042
14.
Histidine residue mediates radical-induced hinge cleavage of human IgG1.
J Biol Chem
; 285(24): 18662-71, 2010 Jun 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-20304919
15.
Enhancing antibody Fc heterodimer formation through electrostatic steering effects: applications to bispecific molecules and monovalent IgG.
J Biol Chem
; 285(25): 19637-46, 2010 Jun 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-20400508
16.
Brain delivery and activity of a lysosomal enzyme using a blood-brain barrier transport vehicle in mice.
Sci Transl Med
; 12(545)2020 05 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32461331
17.
Extended disordered proteins: targeting function with less scaffold.
Trends Biochem Sci
; 28(2): 81-5, 2003 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-12575995
18.
How different are structurally flexible and rigid binding sites? Sequence and structural features discriminating proteins that do and do not undergo conformational change upon ligand binding.
J Mol Biol
; 365(1): 257-73, 2007 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-17059826
19.
Sequence and structure analysis of parallel beta helices: implication for constructing amyloid structural models.
Structure
; 14(6): 1059-72, 2006 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-16765899
20.
Computational study of the fibril organization of polyglutamine repeats reveals a common motif identified in beta-helices.
J Mol Biol
; 358(1): 330-45, 2006 Apr 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-16503338